One of the earliest classes of substances put forward seriously as drugs against aging are the antioxidants, Vitamin E and BHT being the most well-known. Antioxidants As Drugs studied include the following: BHT, ethoxyquin, DDC, Vitamin E, MEA, Diaminodiethyl DS, NDHGA (nordihydroguaretic acid).

Of all the drugs we have considered, the two best prospects as antioxidants against aging are probably NDHGA and BHT. For human use against aging, we lack all knowledge of just what dosage will give the same effect on aging in human beings as the doses given to mice affect their aging. As with the other antiaging drugs, the best suggestion would be to assume an increase of dosage by the 2/3rds power of body weight.