Pregnenolone is a steroid hormone produced in the cells of both the adrenal gland and the central nervous system, and synthesized directly from cholesterol. Pregnenolone is the “grandmother hormone” of all steroid hormones in the body. It, along with DHEA, sits atop what is known as the hormonal cascade. Pregnenolone acts as a precursor to our essential steroid hormones such as DHEA, Testosterone, Estrogen, Glucocorticoids, Mineralocorticoids and therefore an ample supply is critical. In other words, it is a prohormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. Pregnenolone is a GABA antagonist and increases neurogenesis in the hippocampus. Pregnenolone has been studied for its effects on health, longevity, and emotional well-being since 1940 s.
Deficiencies in the above hormones can be normalized just by adding Pregenenolone to the treatment regimen. Pregnenolone also has significant direct effects:
- Fights the effects of fatigue and stress
- Relieves arthritis pain
- Improves heart health
- Boosts the immune system
- Protects against coronary artery disease
- Improves mood and memory
- Essential to full brain function
- Protects against Alzheimer’s disease
What is pregnenolone supplementation used for
- Memory Enhancement
- Fatigue Buster
- Stress Reliever
- Anti Depressant and Mood Enhancer
- Arthritis Treatment and the Treatment of other Rheumatological Diseases
- Nerve Regeneration
- May offer post-menopausal women a natural estrogen replacement therapy.
As with DHEA and other anti-aging hormones, the production of pregnenolone declines with age. Research will almost certainly prove that pregnenolone replacement therapy can slow the aging process. Many scientists and doctors believe that restoring pregnenolone to youthful levels is a powerful anti-aging strategy for both body and brain. Pregnenolone supplementation is natural and physically harmonious, according to Eugene Roberts, Ph.D., a neurobiologist at the City of Hope Medical Center in Los Angeles. The best thing about pregnenolone is that it is completely natural.
