HGH Release Review
Boost hGH Levels by up to 400% with 3rd Generation hGH!
“It contains ingredients not found in our competition’s products like a Glucose Polymer matrix and patented Bioperine (which increase absorption of the active ingredients by over 340%). Our product also contains Broad bean extract which natural nourishes hGH levels all by itself according to Ronald Klatz, M.D.. We also included the more potent version of L-Arginine known as Arginine Pyroglutamate, Alpha-GPC, and much more. Our 3rd Generation formula is much more advanced than its competitors”
The ingredients in our 3rd Generation hGH:
| Supplement Facts Servings per container: 30 |
| Amount Per Serving | % Daily Value |
| Proprietary Blend of: L-Glutamine, Arginine Pyroglutamate, Glucose Polymers, GABA, L-Lysine, Alpha GPC, L-Glysine, Ornithine Alpha-Ketogluaric (OKG), Colostrum, Anterier Pituitary (extract), DMAE, Broad Bean, Bioperine®. | 2895 mg | * |
| Vitamin B5 (Pantothenic Acid)Calories
Carbohydrates |
10 mg2
< 1 g |
100%1%
< 1% |
|
*Daily value not established. |
Alpha-GPC
Alpha-GPC, short for L-alpha-glycerylphosphorylcholine, is an Acetylcholine precursor derived from soy. According to biochemist Jeffrey Reinhardt, M.Sc., one of the world’s leading researchers and authorities on natural hGH secretagogue activity, Alpha-GPC is in a class by itself, helping to nutritionally support five important functional benefits.
ALPHA-GPC Benefits:
1. Supports endogenous hGH levels naturally 2. Delivers more strength from training programs 3. Stimulates cognitive functions 4. Supports coordination when combined with practice 5. Elevates blood levels of choline to support lipotropic functions (methyl group transfers) in the liver.
The Inner Workings Of Alpha-GPC
To understand how Alpha-GPC works, you must first know that HGH secretion is under complex neurotransmitter and hormonal control in your body. For example, a hormone called Growth Hormone Releasing Factor (GHRF) is released from the hypothalamus, which in turn stimulates hGH secretion from the pituitary [See Figure 1]. On the other hand, the hypothalamic hormone Somatostatin inhibits hGH release. With increased stress (such as weight training) or aging, there is a widening imbalance between “good” (stimulatory GHRF) and “bad” (inhibitory Somatostatin) activity on hGH secretion. The result is usually enhanced Somatostatin action and decreased hGH release, which is something no bodybuilder or fitness disciple wants. Part of the reason for this imbalance is a concurrent decrease in levels of the neurotransmitter Acetylcholine2, which has been shown to play an important role in the control of hGH secretion from the pituitary. Research demonstrates that substances that decrease Acetylcholine activity diminish hGH release, while those that increase Acetylcholine transmission potentiate the stimulatory effect of GHRF.
So, increasing GHRF by decreasing Somatostatin release is an extremely novel and effective approach for increasing hGH levels. And Acetylcholine, which is vital for muscle strength, stamina and coordination, seems to be the key! Biochemist and Microbiologist Jeffrey Reinhardt, M.Sc. is a leading researcher, consultant and author in health and nutrition, Jeff Reinhardt is a former Fellow in Nutritional Biochemistry and Fitness at The World Life Research Institute, founder of People For Pure Foods and head of Winners Unlimited Performance Enhancement Programs for Athletes.
Arginine Pyroglutamate
Growth Hormone Effects: Arginine supports the secretion of growth hormone. In fact, a 5 to 10 gram intravenous infusion of arginine is used as a standard endocrinological test to provoke the pituitary into releasing growth hormone. A study at the University of Turin, Italy, showed that even though people in their seventies had lower response than either children or young adults to arginine, the nutrient still boosted their blood levels of hGH to triple the average for their age group. Arginine also helps to improve exercise performance, because it is one of the main ingredients, along with glycine, that the liver uses to make creatine. Supplements of creatine monohydrate are very popular in the bodybuilding community because they raise the level of high-energy creatine phosphates within the muscle and nerve cells needed for high-intensity, short-duration exercises. With arginine you get higher growth hormone levels and the raw material for increasing your energy. Arginine promotes higher hGH levels by blocking the secretion of the growth-hormone inhibitor somatostatin. It also greatly enhances the effect of growth hormone-releasing hormone when they are given together.
L-Glutamine
Glutamine is the latest amino acid to generate excitement as a hGH-releaser thanks to a 1995 study by Thomas C. Welboume of Louisiana State University College of Medicine in Shreveport. Welbourne showed that glutamine raised growth hormone levels more than four times over that of a placebo. Even more exciting, age did not diminish the response at least in this small study of volunteers, who ranged from thirty-two to sixty-four years. Glutamine is the amino acid that is most used by the body, particularly during times of stress. The immune system and the gut practically live on glutamine. If the body does not produce enough glutamine, muscle loss and immune dysfunction can occur. The gut atrophies, meaning nutrients all kinds cannot be absorbed as well as before. A 1993 study by Welbourne in animals showed that glutamine supplementation protects muscle mass and prevents acidosis, which occurs with strenuous exercise and causes muscle breakdown. According to Tudy Shabert, M.D., author of The Ultimate Nutrient Glutamine, supplementation with glutamine, especially in times of stress, would prevent muscle wasting. In a foreword to the book, Douglas Wilmore, M.D., of Harvard Medical School, points out that glutamine is a key to the metabolism and maintenance of muscle, the primary energy source for the immune system, and essential for DNA synthesis, cell division, and cell growth, all factors that are enhanced by HGH. It also crosses the blood-brain barrier into the brain, where it increases energy and mental alertness. Higher levels of glutamine in the blood translates into greater health as a 1994 study showed. In a survey of thirty-three people over the age of sixty, those at the top of the scale of blood glutamine levels had fewer illnesses, lower cholesterol, lower blood pressure, and were closer to their ideal weights than people at the bottom of the scale in this nutrient. The low-glutamine subjects had higher rates of arthritis, diabetes, and heart disease, while those who were high in glutamine said that they felt great.
L-Glycine
Two studies found that this amino acid helps support hGH in the serum. In one, 2 grams at bedtime caused an three-fold increase, while a Japanese research team showed that L-Glycine raised hGH levels ten times over baseline in patients who had gastric surgery. An oral dose of 250 milligrams in normal volunteers also showed a significant, but less pronounced, rise in hGH. They conclude that “the facts demonstrated that glycine is one of the stimulatory agents inducing the pituitary gland to help secrete hGH.” Glycine has also been found useful in increasing output in exercise workouts.
Gama Aminobutyric Acid (GABA)
GABA was designed to help decrease body fat levels and increase lean muscle tissue by stimulating the brain to secrete increased amounts of Human Growth Hormone (hGH). GABA was discovered in 1970, as a synthetic compound capable of passing the blood-brain barrier and useful as an anterior pituitary stimulant. Later studies demonstrated GABA to be a potent neurotransmitter and to be an effective potentiator of secretions of Growth Hormone in clinical studies.
GABA has been clinically proven to help the pituitary gland to secrete Human Growth Hormone in numerous studies. A second important role GABA plays for athletes can be seen in its support of normal responses to training stress. Athletes training and competing using GABA can expect to experience less discomfort and generally exhibit a higher threshold of pain tolerance. GABA has also been demonstrated to promote more restful sleep.
Anterier Pituitary (imported from New Zealand)
Anterior pituitary peptides are small-patented protein peptide molecules. When these peptides are delivered to the pituitary or the hypothalamus they are able to bind to specific receptor sites and stay there for a prolonged period of time. These receptors are the ones involved in the regulation of the activity related to the hypothalamic pituitary axis-the hormone system that controls hGH levels.
L-Lysine
Lysine is an amino acid that is concentrated in muscle tissue and is essential for normal growth and development, as well as energy production. It is also involved in the body’s absorption of calcium, making it crucial for the health of bones and teeth. Taking L-Lysine increases the effect of Arginine Pyroglutamate.
Do not use L-Lysine with L-Arginine .
L-Arginine & L-Lysine compete for the same receptors, Arginine Pyroglutamate attaches to a different receptor allowing for synergistic effect. According to a 1981 study by Italian researcher A. Isidori, M.D., and his associates at the University of Rome, the combination of L-Lysine & Arginine Pyroglutamate, in 15 male volunteers, was 10 times more effective than taking L-Arginine alone .
Lysine has a synergistic effect with Arginine Pyroglutamate.
Arginine Pyroglutamate must be used with L-Lysine. L-ornithine-alpha-ketoglutarate (OKG)
OKG is a precursor to glutamine, OKG has dramatic effects stimulating release of HGH . In France, it is used to rebuild the body tissue after surgery, trauma, burns, and other body-wasting conditions. There is reason to believe combining arginine and ornithine has synergistic effect and supports HGH levels. This unique combination helps to build muscle. By taking them together at bedtime, you stop the body from breaking down muscle tissue as it ordinarily would during the 7-8 hour period you are sleeping.
Broad Bean Extract
Broad beans are a natural source of L-dopa. While L-dopa is an amino acid that occurs naturally in the body, it is only available by prescription. Dr. Klatz in Grow Young With HGH has this to say about L-dopa – “L-dopa is one of the most effective GH-stimulators in both animals and humans.”
Colostrum (Imported from New Zealand)
Research has shown that Colostrum contains powerful natural immune and growth nutrient factors (IGF-1) that bring the body to a state of homeostasis — its powerful, vital natural state of health and well being. Colostrum helps support healthy immune function; it also enables us to resist the harmful effects of pollutants, contaminants and allergens where they attack us. Plus, the growth factors in Colostrum create many of the positive “side-effects” of a healthy organism — an enhanced ability to metabolize or “burn” fat, greater ease in building lean muscle mass, and enhanced rejuvenation of skin and muscle.
DMAE (2-Dimethylaminoethanol)
* DMAE is a chemical naturally produced in the human brain. It is used by the body to convert choline to the neurotransmitter, acetylcholine (i.e., it is a precursor to acetylcholine). This is the basis for thinking that supplementing with DMAE will enhance brain activity. * DMAE extends the lifespan of mice by 27-49%. *
DMAE increases the body’s production of energy and persons using DMAE subjectively report increases in their levels of energy. *
DMAE users experience a sounder Sleep (after 6 weeks subjects reported waking earlier and having a clearer mind upon waking).
Note: DMAE is added along with vitamin B5 to dramatically increase the effectiveness of Arginine Pyroglutamate. They work together to create a synergistic effect.
Glucose Polymer Matrix
Polymers of all types have been used in recent years to allow delicate molecules to survive a difficult journey. Z-Labs hGH Release uses a Glucose Polymer Matrix to protect the amino acids in the supplement. Basically, these polymers coat the amino acids and allow them to pass through the stomach with minimal destruction. This is a key piece of technology that allows our product to have such a powerful effect.
(U.S. Patent Numbers: 5,536,506, 5,744,161, 5,972,382, and 6,054,585)
Bioperine is a standardized piperine extract obtained from the fruits of the Piper nigrum L. (black pepper) and/or Piper longum L. (long pepper) plants that are cultivated in the damp, nutrient-rich soil regions of south India. The delicate pepper berries are hand harvested just prior to ripening and then sun dried to assure optimum maturity and quality.
The extract of piperine, developed by Sabinsa Corporation in its patented form of Bioperine, has been clinically tested in the United States and shown to significantly enhance the absorption of virtually every vitamin, mineral, amino acid, etc.
Bioperine exemplifies a nutraceutical which is not only an important part of human and animal nutrition, but also has become increasingly attractive to modern pharmacologists. This is one ingredient that has been specifically designed to change the way your body looks at supplements.
